Біохімічні механізми впливу свинцю на клітини крові щурів
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the cells. Biochemical effect of Plumbum action upon erythrocytes and lymphocytes in rats, subjectect to parental injection of Lead Acetate (10mg/kg) were analysed. Pb2+ caused erythro- and lymphopoesis' abnormalities in rat organism, violations of synthesis of haemoglobin and its oxygen-transport functions.
It was defined the disruptions of energetic metabolism in rat erythrocytes and lymphocytes of peripheral blood after Lead Acetate injection. Pb-cations activated lipid peroxidation in the cells. Contrary to this, the activity of antioxidant enzymes was decreased.
We identified the correcting effect of vitamin E upon lipid peroxidation and activity of antioxidant enzymes in Pb-cations treated rat blood cells. Key words: Pb2+, erythrocytes, lymphocytes, metabolism, haemopoesis.Скачать